Key result
Increased pulmonary venous resistance in critically ill patients can cause acute pulmonary edema without left ventricular volume overload, confounding diagnoses of circulatory overload.
Answers are grounded in this paper and cite their sources.
In septic patients, radiographic pulmonary edema may result from increased pulmonary venous resistance due to endotoxemia rather than left ventricular volume overload, cautioning against premature cessation of volume expansion.
In patients with sepsis, the presence of radiographic evidence of pulmonary edema may not necessarily indicate the fluid overload. The increased pulmonary venous resistance by endotoxemia can develop pulmonary edema in the absence of left ventricular volume overload. Development of pulmonary edema in this situation can contribute to less aggressive efforts of intravascular volume expansion, thus leading to hypovolemia.
No takes yet. Share an insight, caveat, or question.
Charles Her (2018) conducted a review in Sepsis and Transfusion-Associated Circulatory Overload. Increased pulmonary venous resistance in critically ill patients can cause acute pulmonary edema without left ventricular volume overload, confounding diagnoses of circulatory overload.
Synapse has enriched 10 related papers. Consider them for comparative context: