Experimental study demonstrates efficient production of 1,3-thiazolane derivatives under solvent-free conditions, highlighting a simple and mild catalytic method.
1,3-thiazolane derivatives are obtained in good to excellent yields by proceeding through a simple, mild, and efficient procedure utilizing activated acetylens, primary amines and isothiocyanates in the presence of catalytic amount of N-formylmorpholine under solvent-free conditions.
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IAU (2026) studied this question.
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