Experimental study demonstrates efficient synthesis of substituted pyrroles using N-formylmorpholine as a green solvent, highlighting an environmentally benign route to diverse heterocycles.
A convenient and efficient procedure for the synthesis of substituted pyrroles has been reported based on three component reactions of primary amines and activated acetylenic compounds in the presence of N-formylmorpholine as a green solvent. The above synthetic procedure offers rapid access to novel and diversely substituted pyrrole derivatives.
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IAU (2026) studied this question.
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