Key result
Irradiation of the canine heart with 10 MeV X rays caused pericardial effusion, myocardial necrosis, and fibrosis, with the greatest damage observed in the right atrium.
Answers are grounded in this paper and cite their sources.
May indicate right atrial vulnerability to irradiation in canines; leaves open translation to human radiotherapy planning.
Ten dogs received a single exposure of 10 MeV X rays to the heart. Five dogs received 1500 rad to the midline and five received 1000 rad. When the dogs expired or were killed 73-85 days after irradiation, their hearts were examined pathologically. The changes most frequently observed were pericardial effusion and in the right atrium, myocardial necrosis, and fibrosis. The data suggest that under the conditions of this experiment, irradiation of the canine heart causes greatest damage to the right atrium.
No takes yet. Share an insight, caveat, or question.
Stryker et al. (1980) studied this question. 10 MeV X rays was evaluated on Pathological changes in the heart. Irradiation of the canine heart with 10 MeV X rays caused pericardial effusion, myocardial necrosis, and fibrosis, with the greatest damage observed in the right atrium.
Synapse has enriched 10 related papers. Consider them for comparative context: