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December 6, 2021Annals of Agricultural and Environmental MedicineOpen Access

Non-invasive haemodynamic assessments among hypertensive patients in a routine family doctor’s office

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Key result

Patients with poorly controlled hypertension exhibited a significantly higher prevalence of high vascular resistance compared to those with well-controlled blood pressure (41.1% vs. 27.7%, p=0.037).

Why the study?

Difficult-to-control blood pressure can stem from a mismatch between hypertensive haemodynamic types and drug classes, warranting investigation into haemodynamic type distribution in an outpatient setting.

Does non-invasive haemodynamic assessment using impedance cardiography identify different haemodynamic profiles between well-controlled and poorly controlled hypertensive patients?

Population

189 consecutive patients with primary hypertension at an outpatient clinic

Comparison

Well-controlled vs poorly controlled hypertension groups

Design

Prospective, observational study

Authors

BTBartosz TrzeciakGdańsk Medical UniversityNMNatalia Marek-TrzonkowskaUniversity of GdańskAMAndrzej MoliszGdańsk Medical University

Discussion

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Member takes

Overview

High vascular resistance links to poor control; leaves open whether impedance cardiography can guide therapy.

Study Design

Type

Cross-Sectional (n=189)

Multicenter

No

Structured PICO

Does non-invasive haemodynamic assessment using impedance cardiography identify different haemodynamic profiles between well-controlled and poorly controlled hypertensive patients?

P
Population
189 patients with primary hypertension visiting a family doctor's office underwent cross-sectional non-invasive haemodynamic assessment to compare profiles between poorly and well-controlled hypertension.
E
Exposure
Non-invasive haemodynamic assessment using impedance cardiography (ICG)
C
Comparator
Well-controlled hypertension (BP <140/90 mmHg, n=94) vs poorly controlled hypertension (BP ≥140/90 mmHg, n=95)
O
Outcome
Distribution of haemodynamic types of hypertension (high output, high vascular resistance, balanced)surrogate

Main Result

Absolute Event Rate: 41.1% vs 27.7%

p-value: p=0.037

Impedance cardiography reveals that poorly controlled hypertensive patients frequently exhibit high vascular resistance, suggesting that tailored, haemodynamic-guided antihypertensive therapy could improve blood pressure control.

Limitations

  • Relatively small number of patients
  • Studied population had various comorbidities (diabetes, coronary artery disease) in addition to hypertension
  • Test was conducted with the patients in a sitting position, which differed from other methodologies
  • Only a single ICG test was performed without visit-to-visit trend analysis
  • Patients came from only a single outpatient clinic, so pharmacotherapy used may differ from other clinics
  • Various comorbidities (diabetes, coronary artery disease) present in the population
  • Test conducted with patients in sitting position
  • Only one ICG test performed per patient (no visit-to-visit trend)
  • Single outpatient clinic

Cite This Study

Trzeciak et al. (2021) conducted a cross-sectional in Primary hypertension (n=189). Poorly controlled hypertension (BP ≥140/90 mmHg) vs. Well-controlled hypertension (BP <140/90 mmHg) was evaluated on High vascular resistance haemodynamic state (p=0.037). Patients with poorly controlled hypertension exhibited a significantly higher prevalence of high vascular resistance compared to those with well-controlled blood pressure (41.1% vs. 27.7%, p=0.037).

synapsesocial.com/papers/6a9429090533089f4392dedahttps://doi.org/10.26444/aaem/143163

Topics

Hypertension management
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Also Consider

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  1. 1Prevalence, awareness, treatment and control of hypertension in the adult Polish population – Multi-center National Population Health Examination Surveys – WOBASZ studies2018 · 79 citations
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  3. 3Value of Noninvasive Hemodynamics to Achieve Blood Pressure Control in Hypertensive Subjects2006 · 100 citations
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