Why the study?
To describe hemodynamic profiles in treatment-naive hypertensive patients versus normotensive controls and evaluate whether hemodynamic-guided therapy improves BP control within 4 weeks.
Does personalized treatment initiation based on hemodynamic profiles improve blood pressure control in newly diagnosed hypertensive outpatients?
Population
80 outpatients with newly diagnosed AHT and 20 age- and sex-matched normotensive controls
Comparison
Concordant treatment vs discordant treatment based on hemodynamic profiles
Design
Exploratory post hoc analysis of a randomized parallel-group trial
Follow-up
4 weeks
Authors
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Hemodynamic-guided initial therapy did not improve 4-week BP control; leaves open whether profiling aids treatment selection in new hypertension.
Does personalized treatment initiation based on hemodynamic profiles improve blood pressure control in newly diagnosed hypertensive outpatients?
Personalized treatment initiation based on noninvasive hemodynamic profiles does not significantly improve blood pressure control in newly diagnosed hypertensive outpatients.
Glinz et al. (2020) studied this question.