Why the study?
What are the long-term outcomes and weight changes following reversal of jejunoileal bypass in patients with morbid obesity?
What are the long-term outcomes and weight changes following reversal of jejunoileal bypass in patients with morbid obesity?
Reversal of jejunoileal bypass resolves most bypass-associated complications but universally leads to significant weight regain.
Supports caution on post-reversal weight regain; leaves open optimal long-term strategies after jejunoileal bypass failure.
Jejunoileal bypass for morbid obesity was performed on 182 patients between 1971 and 1982. At 19 years' follow-up 60 (33 per cent) have had to undergo reversal. The compelling reasons for reversal were life-threatening malnutrition, immune complex disease, renal oxalate stones, osteomalacia and severe electrolyte disturbance. All patients gained weight after reversal of the jejunoileal bypass; most gained all the weight they had lost. Thirty-one patients returned to grade III obesity and 14 to grade II. Twelve patients had an associated vertical gastroplasty: ten regained their previous weight and only two stayed within normal weight. Patients were generally free from bypass-associated symptoms and complications apart from arthralgia and arthritis. This report concludes a series of articles published by the authors on jejunoileal bypass over the past 20 years describing the rise and fall of this surgical procedure.
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Anderson et al. (1994) studied this question.
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