Population
Nerve growth factor (NGF)-treated rat phaeochromocytoma PC12 cells
Design
Preclinical
Authors
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Should not alter clinical practice; leaves open whether distinct binding sites and open states apply beyond PC12 cells.
ATP and nicotine appear to activate the same ion channels in PC12 cells but through different binding sites and with different open-state properties.
Nakazawa et al. (1991) studied this question.
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