Key result
Systemic use of nicotine packs with moderate nicotine content (up to 6 mg) caused relatively small changes in heart rate variability compared to other nicotine delivery systems.
Why the study?
Do different nicotine delivery systems and smoking simulators affect heart rate variability in healthy volunteers?
Observational (n=10)
No
Do different nicotine delivery systems and smoking simulators affect heart rate variability in healthy volunteers?
Nicotine packs of oral fixation with moderate nicotine content (up to 6 mg) cause relatively small acute changes in heart rate variability compared to other nicotine delivery systems.
n this experimental study heart rate variability (HRV) using electrocardiography was studied in a small group of volunteers (10 people) who have never smoked (4), ex-smokers (4) and active smokers (2). Different nicotine delivery systems and smoking simulators, including regular, nicotine-free and electronic cigarettes, tobacco heating systems, chewing gums and a completely new product on the domestic market – nicotine packs of oral fixation (NPOF) were used. Supplemented with hormonal studies (stress hormones in saliva and catecholamines in the blood), HRV analysis showed relatively small changes in HRV with systemic use of packs with moderate nicotine content (up to 6 mg), which makes this type of product a leader in biological safety among the studied alternative delivery systems nicotine.
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Menshov et al. (2020) conducted an observational in Healthy volunteers (n=10). Nicotine packs of oral fixation (NPOF) and other nicotine delivery systems vs. Regular cigarettes, nicotine-free cigarettes, e-cigarettes, tobacco heating systems, chewing gums was evaluated on Heart rate variability (HRV) parameters. Systemic use of nicotine packs with moderate nicotine content (up to 6 mg) caused relatively small changes in heart rate variability compared to other nicotine delivery systems.
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