Key result
Amrinone and enoximone both significantly increased cardiac index (to 2.5 and 2.6 L/min/m2, respectively) in patients with low-output syndrome after heart surgery, with no significant differences.
Why the study?
Does amrinone compared to enoximone improve haemodynamics in patients with low-output syndrome after heart surgery?
RCT (n=19)
randomized
Does amrinone compared to enoximone improve haemodynamics in patients with low-output syndrome after heart surgery?
Both amrinone and enoximone are feasible as monotherapy for severe cardiac low-output states after heart surgery, effectively improving haemodynamics without significant differences between the two agents.
Authors
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Either agent is suitable monotherapy for post-heart surgery low-output syndrome; confirms hemodynamic equivalence in this RCT.
Zerkowski et al. (1992) conducted an RCT in Severe cardiac low-output states after heart surgery (n=19). Amrinone vs. Enoximone was evaluated on Cardiac index. Amrinone and enoximone both significantly increased cardiac index (to 2.5 and 2.6 L/min/m2, respectively) in patients with low-output syndrome after heart surgery, with no significant differences.
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