Key result
Enoximone significantly improved hemodynamic performance in refractory postcardiotomy cardiogenic shock, increasing cardiac index from 1.56 to 2.72 l/min/m2 (p<0.001).
Why the study?
Does enoximone improve hemodynamic parameters in patients with refractory postcardiotomy cardiogenic shock?
Population
13 patients with severe postcardiotomy low cardiac output syndrome refractory to conventional treatment.
Design
Case_series
Follow-up
Until hospital discharge or death
Authors
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Should not yet change practice in refractory postcardiotomy cardiogenic shock; hypothesis-generating pending controlled trials.
Observational (n=13)
Does enoximone improve hemodynamic parameters in patients with refractory postcardiotomy cardiogenic shock?
Absolute Event Rate: 2.72% vs 1.56%
p-value: p=<0.001
Enoximone significantly improves hemodynamic performance in patients with severe postcardiotomy cardiogenic shock refractory to conventional therapies.
Iversen et al. (1992) conducted an observational in Postcardiotomy cardiogenic shock (n=13). Enoximone vs. Baseline (pre-treatment) was evaluated on Cardiac index (p=<0.001). Enoximone significantly improved hemodynamic performance in refractory postcardiotomy cardiogenic shock, increasing cardiac index from 1.56 to 2.72 l/min/m2 (p<0.001).
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