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The study demonstrates a rapid development of natural immunity to poliovirus at an early age in Ghana, peaking at 4-6 years.
By neutralization test 213 serum samples were tested to determine the natural immunity status to poliovirus in Accra. Samples were collected from the following age groups: (1) 0–1 yr., (2) 2–3 yrs., (3) 4–6 yrs., (4) 11–15 yrs., (5) 16–20 yrs., (6) 21 yrs. and above. At the early age of life (2–3 yrs.) polio antibody was found in more than 65% to all the 3 types of poliovirus. At the age of 4–6 years, immunity reached its peak with 86, 88 and 93% against poliovirus types 1, 2 and 3 respectively. In Ghana a rapid development of antibodies at an early age characterizes the pattern obtained.
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Pácsa et al. (1971) studied this question.
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