Key result
Optimized beta-blocked heart failure patients achieved a significantly lower peak heart rate during exercise compared to sedentary controls (65.4% vs 98.6% of maximum predicted for age; p<0.0001).
Why the study?
Does a treadmill cardiopulmonary exercise test reveal different heart rate dynamics in optimized beta-blocked heart failure patients compared to sedentary normal individuals?
Observational (n=39)
Does a treadmill cardiopulmonary exercise test reveal different heart rate dynamics in optimized beta-blocked heart failure patients compared to sedentary normal individuals?
Absolute Event Rate: 65.4% vs 98.6%
p-value: p=<0.0001
In optimized beta-blocked heart failure patients, a peak heart rate over 65% of the age-adjusted maximum during exercise testing should be considered near-maximal effort, as they do not reach traditional age-predicted maximums despite a normal percentage increase from baseline.
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May indicate near-maximal effort at >65% age-predicted HR in beta-blocked HF on CPET; leaves open need for revised normative thresholds.
Carvalho et al. (2008) conducted an observational in Heart failure (n=39). Optimized beta-blocked heart failure vs. Sedentary normal individuals was evaluated on Peak heart rate (% maximum predicted for age) (p=<0.0001). Optimized beta-blocked heart failure patients achieved a significantly lower peak heart rate during exercise compared to sedentary controls (65.4% vs 98.6% of maximum predicted for age; p<0.0001).
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