Population
WI-26 cells and Green African monkey kidney cells (MKC) infected with rhinovirus strains 1059 and HGP
Design
Preclinical
Follow-up
up to 15 hours
Authors
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Receptor-mediated tropism restricts viral replication in heterologous cells; leaves open receptor-targeted strategies for human rhinovirus.
The inability of rhinovirus strain 1059 to multiply in monkey kidney cells is due to a lack of receptors for adsorption, whereas HGP can infect both WI-26 and MKC.
Haff et al. (1966) studied this question.
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