Population
Human embryonic diploid cells (WI-38) infected with five rhinoviruses (1A, 2, 6, 13, 17)
Comparison
Freshly prepared methylcellulose overlay vs Agar overlay (for Mg++ enhancement comparison)
Design
Preclinical
Follow-up
6 to 14 days of incubation
Authors
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May enable standardized rhinovirus quantification in vitro; leaves open clinical translation pending further validation.
A sensitive and reliable plaque assay system using methylcellulose overlay was developed for rhinoviruses in human embryonic diploid cells.
Dolan et al. (1968) studied this question.
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