Why the study?
Is active myocarditis associated with the development of heart failure in patients with chronic Chagas' disease?
Population
38 patients with chronic Chagas' disease diagnosed serologically, divided into three clinical groups: Group…
Comparison
Endomyocardial biopsy evaluation for active… vs Comparison across three clinical severity groups
Design
Cross-sectional
Authors
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Active myocarditis was associated with heart failure in chronic Chagas disease; hypothesis-generating for anti-inflammatory therapy, requiring prospective confirmation.
Is active myocarditis associated with the development of heart failure in patients with chronic Chagas' disease?
Active myocarditis plays an important role in the development of heart failure in chronic Chagas' disease, suggesting a potential role for early anti-inflammatory therapy.
Higuchi et al. (1987) studied this question.
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