Why the study?
Are anti-myocardial antibodies pathogenically important in the evolution of dilated or chagasic myocardiopathies?
Population
30 patients undergoing right ventricular endomyocardial biopsy and 5 necropsy samples from patients with…
Design
Cross-sectional
Authors
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Does not support pathogenic role of anti-myocardial antibodies in cardiomyopathies; hypothesis-generating and should not change practice.
Are anti-myocardial antibodies pathogenically important in the evolution of dilated or chagasic myocardiopathies?
The absence of immunoglobulin and complement deposition in myocardial biopsies does not support the pathogenic role of anti-myocardial antibodies in dilated or chagasic cardiomyopathies.
Higuchi et al. (1986) studied this question.
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