Key result
Immunoperoxidase and immunofluorescence techniques showed complete agreement in detecting autologous deposits of immunoglobulins and complement in all 4 patients with chronic Chagas' myocardiopathy.
Why the study?
Does the immunoperoxidase technique agree with immunofluorescence in detecting autologous deposits in patients with chronic Chagas' myocardiopathy?
Population
4 patients suffering from chronic Chagas' myocardiopathy (ChrCHM), ages 39 to 52 years (mean 48.5 years).
Comparison
Immunoperoxidase technique on right… vs Direct immunofluorescence examination
Design
Case_series
Authors
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Should not yet change diagnostic practice in Chagas' myocardiopathy; leaves open validation in larger cohorts.
Observational (n=4)
Does the immunoperoxidase technique agree with immunofluorescence in detecting autologous deposits in patients with chronic Chagas' myocardiopathy?
The immunoperoxidase technique is a reliable method that agrees with immunofluorescence for detecting autologous immunological deposits in chronic Chagas' myocardiopathy.
Molina et al. (2008) conducted an observational in Chronic Chagas' myocardiopathy (n=4). Immunoperoxidase and immunofluorescence techniques was evaluated on Agreement between immunofluorescence and immunoperoxidase techniques in evidencing autologous deposits. Immunoperoxidase and immunofluorescence techniques showed complete agreement in detecting autologous deposits of immunoglobulins and complement in all 4 patients with chronic Chagas' myocardiopathy.
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