Population
Cardiac myosin and its heavy meromyosin labeled with N-methyl-2-anilino-6-naphthalenesulfonyl group
Comparison
Addition of F-actin vs Baseline (without F-actin)
Design
Preclinical
Authors
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Actin binding may stabilize cardiac myosin conformation; leaves open functional relevance for contractility in physiological models.
The binding of actin to cardiac myosin makes the protein matrix around the subfragment-1/subfragment-2 link region less mobile.
Toshiaki Hiratsuka (1983) studied this question.
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