Key result
Platelet-to-lymphocyte ratio was significantly higher in patients with isolated coronary artery ectasia (123) than in those with normal angiograms (100) and obstructive CAD (110).
Why the study?
Is platelet-to-lymphocyte ratio associated with the presence and severity of coronary artery ectasia?
Observational (n=330)
Is platelet-to-lymphocyte ratio associated with the presence and severity of coronary artery ectasia?
Platelet-to-lymphocyte ratio is significantly associated with the presence and severity of coronary artery ectasia, suggesting a potential role as an easily available inflammatory marker for this condition.
PLR may reflect inflammation in isolated CAE; leaves open its prognostic value or role in management.
OBJECTIVE: The aim of this study was to investigate the relationship between platelet-to-lymphocyte ratio (PLR), an easily available inflammatory marker, and coronary artery ectasia (CAE). METHODS: After applying the exclusion criteria, the retrospective study population consisted of 330 patients, including 110 patients with isolated CAE, 110 with obstructive coronary artery disease (CAD), and 110 with normal coronary artery angiograms (NCA). The severity of isolated CAE was determined according to the Markis classification. SPSS 22.0 statistical package program was used for data analysis. RESULTS: PLR was significantly higher in patients with isolated CAE than in those with NCA and obstructive CAD [123 (113-156), 100 (86-138), and 110 (102-141), respectively]. Logistic regression analysis showed that PLR and C-reactive protein level were significantly correlated with the severity of isolated CAE. CONCLUSION: To the best of our knowledge, this study showed for the first time that PLR was significantly associated with CAE.
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Harun Kundi (2016) conducted an observational in Coronary artery ectasia (n=330). Platelet-to-lymphocyte ratio vs. Normal coronary artery angiograms and obstructive CAD was evaluated on Presence and severity of coronary artery ectasia. Platelet-to-lymphocyte ratio was significantly higher in patients with isolated coronary artery ectasia (123) than in those with normal angiograms (100) and obstructive CAD (110).
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