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January 1, 2021Journal of Translational AutoimmunityOpen Access

Diagnosis and treatment of eosinophilic myocarditis

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Key result

Eosinophilic myocarditis diagnosis relies on endomyocardial biopsy and CMR, while early glucocorticoid and anticoagulant therapy may prevent intermediate disease stage development.

Population

Patients with eosinophilic myocarditis

Design

Review

Authors

ZZZezhong ZhongZYZicong YangYPYiming Peng

Discussion

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Overview

Gene associations in eosinophilic myocarditis are hypothesis-generating; larger studies needed before clinical translation.

Structured PICO

P
Population
Patients with eosinophilic myocarditis
I
Intervention
Diagnosis (endomyocardial biopsy, CMR imaging) and treatment (glucocorticoids, anticoagulant therapy)

This review highlights the importance of endomyocardial biopsy and CMR for diagnosing eosinophilic myocarditis, and the role of early glucocorticoid and anticoagulant therapy in preventing disease progression.

Limitations

  • The accurate myocarditis incidence rate is difficult to determine because of the clinical limitations of an endomyocardial biopsy.

Cite This Study

Zhong et al. (2021) conducted a review in Eosinophilic myocarditis. Eosinophilic myocarditis diagnosis relies on endomyocardial biopsy and CMR, while early glucocorticoid and anticoagulant therapy may prevent intermediate disease stage development.

synapsesocial.com/papers/6a950dce77bd7906860f326chttps://doi.org/10.1016/j.jtauto.2021.100118
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Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Cardiovascular Magnetic Resonance in Myocarditis: A JACC White Paper2009 · 2,525 citations
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  3. 3Novel technique for the direct flow cytofluorometric analysis of human basophils in unseparated blood and bone marrow, and the characterization of phenotype and peroxidase of human basophils1999 · 67 citations
  4. 4A Clinical Trial of Immunosuppressive Therapy for Myocarditis1995 · 1,284 citations