Why the study?
Does G-CSF enhance the migration of human mesenchymal stem cells towards SDF-1?
Does G-CSF enhance the migration of human mesenchymal stem cells towards SDF-1?
G-CSF enhances the migration of human mesenchymal stem cells towards SDF-1 in a CXCR4-independent manner, suggesting a potential strategy for directing stem cells for cardiac repair.
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G-CSF may enhance hMSC homing; hypothesis-generating for cardiac repair, requiring in vivo confirmation before any clinical consideration.
Bolno et al. (2004) studied this question.
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