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November 1, 1993Experimental Physiology

The effect of the putative AT2 agonist, p‐aminophenylalanine6 angiotensin II, on thirst and sodium appetite in rats

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Authors

ACAS CooneyPhysiological Society JFJT FitzsimonsPhysiological Society

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Implication

Questions putative central AT2 agonists' efficacy on thirst; leaves open receptor subtype roles in fluid homeostasis.

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Cite This Study

Cooney et al. (1993) studied this question.

synapsesocial.com/papers/6a9533e8d3e7ac3765e3c5cf https://doi.org/10.1113/expphysiol.1993.sp003724

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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Intracerebroventricular angiotensin II‐induced thirst and sodium appetite in rat are blocked by the AT1 receptor antagonist, Losartan (DuP 753), but not by the AT2 antagonist, CGP 42112B1992 · 90 citations
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3Median Preoptic AT1a Receptor Knockdown Does Not Diminish Drinking in Response to Peripheral Angiotensin II Administration2016
4Subtype 2 of angiotensin II receptors controls pressure-natriuresis in rats.1995 · 139 citations
5Angiotensin II AT<sub>2</sub>receptors inhibit proximal tubular Na<sup>+</sup>-K<sup>+</sup>-ATPase activity via a NO/cGMP-dependent pathway2005 · 72 citations