Mechanical forces induce myofibroblast differentiation and SMA expression via the Rho-Rho-kinase-LIMK cofilin pathway and MRTF-A nuclear translocation.
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May guide antifibrotic targeting of MRTF-A/Rho kinase; leaves open translation from animal models to human fibrosis.
Zhao et al. (2007) studied this question.
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