Key result
Enterovirus D68 was detected in a 6-year-old boy presenting with acute flaccid myelitis, representing the first reported case of EV-D68-associated AFM in mainland China.
Why the study?
Although an increasing number of acute flaccid myelitis cases have been reported with enterovirus D68 infection in the US, few such cases have been found in China.
Case Report (n=1)
This report documents the first confirmed case of Enterovirus D68-associated acute flaccid myelitis in mainland China, emphasizing the need for dedicated surveillance systems.
Supports EV-D68 testing in AFM cases in China; extends geographic evidence and leaves open need for systematic surveillance.
BACKGROUND: Acute flaccid myelitis (AFM) are reported to be associated with enterovirus D68 infection. Though an increasing number of AFM cases were reported with EV-D68 infection in the US, few such cases have been found in China. CASE PRESENTATION: A 6-year-old boy presented with acute flaccid myelitis (AFM) involving left arm after fever and respiratory symptoms for 6 days. Computed Tomography (CT) revealed inflammation in both lungs and magnetic resonance imaging (MRI) of the brain and spine showed swelling in the left frontal lobe and brain stem. The patient was diagnosed with meningomyelitis. EV-D68 was detected from pharyngeal samples 36 days after the onset of the disease. CONCLUSION: We report the first EV-D68 infection in case of AFM in mainland China. AFM surveillance systems is recommended to be established in China to guide diagnosis, case reporting, and specimen collection and testing for better understanding its etiologies.
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Wang et al. (2020) conducted a case report in Acute flaccid myelitis (n=1). Enterovirus D68 infection was evaluated on Clinical presentation and viral detection. Enterovirus D68 was detected in a 6-year-old boy presenting with acute flaccid myelitis, representing the first reported case of EV-D68-associated AFM in mainland China.
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