Key result
Analysis of 9,251 RVA strain sequences across 86 animal species demonstrated a broad host range and the potential to generate highly virulent zoonotic variants through gene reassortments.
Why the study?
Rotavirus species A causes acute diarrhea in children and young animals with severe economic losses, warranting an analysis of RVA genomic constellations described in animal hosts.
Population
RVA described in 86 animal species including animal RVA strains in humans
Design
Review
Authors
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Raises awareness for potential zoonotic RVA transmission; leaves open the full scope of interspecies reassortment and surveillance needs.
Rotavirus species A exhibits a broad host range across 86 animal species, highlighting the potential for zoonotic transmission to humans through gene reassortment.
Alarcón et al. (2022) conducted a review in Rotavirus species A (RVA) infection. Zoonotic RVA was evaluated on RVA genomic constellations and host distribution. Analysis of 9,251 RVA strain sequences across 86 animal species demonstrated a broad host range and the potential to generate highly virulent zoonotic variants through gene reassortments.
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