Key result
Surgical aortic valve replacement in octogenarians was associated with a very low operative mortality (1.9%) that was comparable to younger patients (2.9%), along with significant improvements in quality of life.
Why the study?
Does surgical aortic valve replacement provide comparable survival and quality of life improvements in octogenarians compared to younger patients with severe aortic stenosis?
Population
762 patients with symptomatic severe aortic stenosis, 21.4% aged >80 years, 49.0% undergoing concomitant…
Comparison
Surgical aortic valve replacement in octogenarians vs Surgical aortic valve replacement in patients…
Design
Cohort
Follow-up
1 year (with unspecified long-term survival follow-up)
Authors
Loading...
SAVR outcomes in this pre-TAVR cohort offer historical benchmarks; leaves open whether contemporary TAVR achieves comparable results in similar patients.
Cohort (n=762)
No
Does surgical aortic valve replacement provide comparable survival and quality of life improvements in octogenarians compared to younger patients with severe aortic stenosis?
Absolute Event Rate: 1.9% vs 2.9%
p-value: p=0.59
Surgical aortic valve replacement in octogenarians is associated with low mortality and significant improvements in quality of life comparable to younger patients, supporting its viability in selected older patients.
Klomp et al. (2016) conducted a cohort in Symptomatic severe aortic stenosis (n=762). Age ≥ 80 years (Octogenarians) vs. Age < 80 years was evaluated on Operative mortality (p=0.59). Surgical aortic valve replacement in octogenarians was associated with a very low operative mortality (1.9%) that was comparable to younger patients (2.9%), along with significant improvements in quality of life.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: