Key result
Transcatheter aortic valve implantation significantly improved health-related quality of life at 13 months, while overall cognitive function remained stable.
Why the study?
The association between cognitive functions and health-related quality of life in patients undergoing TAVI for severe aortic stenosis is still unclear.
Does transcatheter aortic valve implantation (TAVI) improve cognitive functions and quality of life in elderly patients with severe aortic stenosis?
Cohort (n=259)
No
Does transcatheter aortic valve implantation (TAVI) improve cognitive functions and quality of life in elderly patients with severe aortic stenosis?
TAVI is associated with preserved cognitive function and significant improvements in health-related quality of life at long-term follow-up in elderly patients with severe aortic stenosis.
Answers are grounded in this paper and cite their sources.
Supports TAVI consideration for QoL gains with cognitive stability in elderly severe AS; leaves open causal confirmation in randomized trials.
INTRODUCTION: Transcatheter aortic valve implantation (TAVI) has emerged as a therapeutic option for patients with severe aortic stenosis (AS). However, an association between cognitive functions (CF) and health-related quality of life (HRQoL) in TAVI patients is still unclear. AIM: To assess the long-term changes in CF and HRQoL in elderly patients with AS after TAVI. MATERIAL AND METHODS: = 85). CF and HRQoL characteristics assessed at baseline and 13 months were compared between groups. The analysis of multiple linear regression was performed to identify the association between HRQoL and CF and to assess the influence of TAVI on HRQoL. Improvements in all five dimensions of HRQoL, from 4.8% in self-care and up to 33.6% in pain/discomfort, were found. At follow-up, 60% of TAVI patients had improved health, 12% had worse health, 4% showed no change and 24% had a "mixed" change. CONCLUSIONS: TAVI is associated with positive changes in the functioning of elderly patients at long-term follow-up.
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Olszewska-Turek et al. (2020) conducted a cohort in Severe aortic stenosis (n=259). Transcatheter aortic valve implantation (TAVI) vs. Baseline (pre-procedure) was evaluated on Health-related quality of life (EQ-5D-3L total score) (p=0.001). Transcatheter aortic valve implantation significantly improved health-related quality of life at 13 months, while overall cognitive function remained stable.
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