Population
9 juvenile domestic sheep
Design
Preclinical
Follow-up
after the 150th postoperative day
Authors
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Supports preclinical chronic mitral valve testing in juvenile sheep; leaves open translation to clinical practice.
This study establishes a successful in vivo juvenile sheep model for the chronic evaluation of prosthetic mitral valves, demonstrating normal function of a new bileaflet valve at 150 days.
Irwin et al. (1993) studied this question.
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