Key result
A history of heart failure was a more important prognosticator for all-cause mortality after coronary artery bypass grafting than ejection fraction, with a higher prevalence and poorer prognosis of HFpEF in women.
Why the study?
Does the presence of HFpEF or HFrEF affect long-term survival in women and men after coronary artery bypass grafting?
Population
40,083 patients who underwent coronary artery bypass grafting in Ontario, Canada, between October 1, 2008…
Comparison
Heart failure with preserved ejection fraction… vs Preserved ejection fraction without HF or…
Design
Cohort
Follow-up
4±2 years
Authors
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HF history may warrant greater weight than EF in post-CABG risk assessment; leaves open whether HFpEF-targeted strategies improve survival in women.
Cohort (n=40,083)
Yes
Does the presence of HFpEF or HFrEF affect long-term survival in women and men after coronary artery bypass grafting?
A history of clinical heart failure is a more important prognosticator for long-term mortality after CABG than ejection fraction alone, highlighting the need for preoperative screening and extended follow-up in these patients.
Sun et al. (2018) conducted a cohort in Coronary artery disease requiring coronary artery bypass grafting (n=40,083). Heart failure with preserved or reduced ejection fraction vs. No heart failure was evaluated on All-cause mortality. A history of heart failure was a more important prognosticator for all-cause mortality after coronary artery bypass grafting than ejection fraction, with a higher prevalence and poorer prognosis of HFpEF in women.
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