Key result
Among 467 healthy blood donors, 9.9% tested positive for autoantibodies to cardiac troponin T, a prevalence similar to that of autoantibodies to the I isoform.
Population
467 apparently healthy blood donors, average age 39.7 years (range 18-72), 47:53 male to female ratio.
Design
Cross-sectional
Authors
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May confound cTnT immunoassay interpretation; leaves open clinical impact in patients with suspected injury.
Cross-Sectional (n=467)
Autoantibodies to cardiac troponin T are present in approximately 9.9% of healthy blood donors, highlighting a potential interfering factor in cTnT immunoassays.
Adamczyk et al. (2009) conducted a cross-sectional in Healthy blood donors (n=467). Autoantibodies to cardiac troponin T was evaluated on Prevalence of positive responders for autoantibodies to cTnT. Among 467 healthy blood donors, 9.9% tested positive for autoantibodies to cardiac troponin T, a prevalence similar to that of autoantibodies to the I isoform.
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