Key result
White-coat hypertension without organ damage was associated with a higher risk of fatal cardiovascular events compared to normotension without organ damage (HR 2.0; 95% CI 1.1-3.6; P=0.02).
Why the study?
Some guidelines suggest white-coat hypertension carries little or no increased cardiovascular risk in the absence of organ damage, but data on this issue were lacking.
Does white-coat hypertension without organ damage increase the risk of mortality, new hypertension, and new organ damage compared to normotension?
Cohort (n=1,423)
Does white-coat hypertension without organ damage increase the risk of mortality, new hypertension, and new organ damage compared to normotension?
Hazard Ratio: 2 (95% CI 1.1–3.6)
p-value: p=0.02
White-coat hypertension without organ damage carries a significantly increased long-term risk of mortality and progression to sustained hypertension or organ damage compared to normotension.
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WCH without OD may warrant closer monitoring; leaves open whether intervention improves outcomes.
A 2022 study conducted a cohort in White-coat hypertension (n=1,423). White-coat hypertension without organ damage vs. Normotension without organ damage was evaluated on Fatal cardiovascular events (HR 2.0, 95% CI 1.1-3.6, p=0.02). White-coat hypertension without organ damage was associated with a higher risk of fatal cardiovascular events compared to normotension without organ damage (HR 2.0; 95% CI 1.1-3.6; P=0.02).
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