Key result
Post-exercise ischemia in hypoxia significantly decreased sympathetic baroreflex sensitivity compared to resting hypoxia (-35 vs -68 % MSNA mmHg-1; P<0.001).
Why the study?
Does metaboreceptor and chemoreceptor activation alter sympathetic and cardiac baroreflex control following exercise in hypoxia in young men?
RCT (n=15)
random order
Does metaboreceptor and chemoreceptor activation alter sympathetic and cardiac baroreflex control following exercise in hypoxia in young men?
Absolute Event Rate: -35% vs -68%
p-value: p=<0.001
Metaboreceptor and chemoreceptor activation exert differential effects on sympathetic and cardiac baroreflex function, with metaboreceptor activation being the major determinant of sympathetic baroreflex sensitivity during hypoxia.
No takes yet. Share an insight, caveat, or question.
Hypothesis-generating for baroreflex modulation in hypoxia; leaves open translation to clinical populations or interventions.
Gujic et al. (2007) reported an RCT. Post-handgrip exercise ischemia in hypoxia vs. Resting hypoxia was evaluated on Sympathetic baroreflex sensitivity (p=<0.001). Post-exercise ischemia in hypoxia significantly decreased sympathetic baroreflex sensitivity compared to resting hypoxia (-35 vs -68 % MSNA mmHg-1; P<0.001).
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