Why the study?
Does PCR detection of CMV DNA in endomyocardial biopsies correlate with systemic infection, myocarditis, or acute rejection in heart transplant recipients?
Population
17 heart transplant recipients undergoing 103 unfixed endomyocardial biopsies during the first 4 months…
Design
Cohort
Follow-up
first 4 months post-transplant
Authors
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CMV DNA detection in EMBs does not signal myocarditis or rejection; leaves open the utility of routine PCR surveillance in heart transplant monitoring.
Does PCR detection of CMV DNA in endomyocardial biopsies correlate with systemic infection, myocarditis, or acute rejection in heart transplant recipients?
PCR frequently detects CMV DNA in endomyocardial biopsies during systemic infection in heart transplant recipients, but this is not associated with myocarditis or increased acute rejection.
Ghisetti et al. (1996) studied this question.
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