Why the study?
Does digoxin administration correlate with specific electrocardiographic changes (PTQ index) and serum digoxin levels in healthy volunteers?
Population
4 healthy volunteers
Design
Case_series
Follow-up
4 weeks
Authors
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PTQ index may track digoxin effect in healthy volunteers; hypothesis-generating and requires validation before any clinical use.
Does digoxin administration correlate with specific electrocardiographic changes (PTQ index) and serum digoxin levels in healthy volunteers?
There is a linear correlation between serum digoxin levels, total body digoxin burden, and specific ECG changes (PTQ index) in healthy individuals.
Joubert et al. (1976) studied this question.
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