Key result
Isolated systolic hypertension was associated with significantly increased intima-media thickness and decreased carotid distensibility compared with age-matched controls.
Why the study?
Does ultrasound RF-data technology detect differences in intima-media thickness and vascular elasticity of the common carotid artery in patients with isolated systolic hypertension compared to normal subjects?
Case-Control (n=80)
Does ultrasound RF-data technology detect differences in intima-media thickness and vascular elasticity of the common carotid artery in patients with isolated systolic hypertension compared to normal subjects?
Ultrasound RF-data technology can quantitatively detect increased intima-media thickness and decreased arterial elasticity in the common carotid artery of patients with isolated systolic hypertension.
Answers are grounded in this paper and cite their sources.
Supports RF-data ultrasound for carotid assessment in isolated systolic hypertension; leaves open whether changes predict outcomes or guide therapy.
BACKGROUND: Radiofrequency (RF) data technology is a newly developed method to evaluate vascular disease, especially subclinical atherosclerotic change. Data regarding predictors of intima-media thickness (IMT) and vascular elasticity of the common carotid artery (CCA) in subjects with isolated systolic hypertension (ISH) using ultrasound RF-data technology are scarce. AIMS: We evaluated the change in IMT and vascular elasticity of the CCA in patients with ISH at an early phase using US RF-data technology. METHODS: Thirty-nine patients with ISH and 41 age-matched control subjects were the study population. The common carotid arterial systolic diameter (Ds), diastolic diameter (Dd), IMT, carotid distensibility (CD), local pulse wave velocity (PWVβ) and stiffness (β) were compared between the two groups, as were correlations between pulse pressure (PP) and parameters of vascular stiffness. RESULTS: Common carotid arterial Ds, Dd, IMT, PWVβ and β increased whereas CD decreased more significantly in the ISH group than in age-matched controls. The level of PP in the ISH group had significant positive correlations with PWVβ (r = 0·298, P<0·05) and β (r = 0·291, P<0·05), whereas significant correlations with CD were not observed. CONCLUSIONS: US RF-data technology could be used to accurately and quantitatively evaluate increased IMT and decreased arterial elasticity of the CCA in patients with ISH compared with normal subjects.
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Dan et al. (2011) conducted a case-control in Isolated systolic hypertension (n=80). Isolated systolic hypertension vs. Age-matched control subjects was evaluated on Intima-media thickness and vascular elasticity of the common carotid artery (Ds, Dd, IMT, CD, PWVβ, and β). Isolated systolic hypertension was associated with significantly increased intima-media thickness and decreased carotid distensibility compared with age-matched controls.
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