Key result
Mean platelet volume was significantly higher in patients with proliferative diabetic retinopathy compared to healthy controls (8.18 vs 7.52 fL, p<0.05) and positively correlated with the degree of retinopathy.
Why the study?
Is mean platelet volume associated with the degree of retinopathy in patients with diabetes mellitus?
Population
120 individuals, including 90 patients with diabetes mellitus and diabetic retinopathy and 30 healthy…
Design
Cross-sectional
Authors
Loading...
Does not support MPV use in diabetic retinopathy care; hypothesis-generating for microvascular complication research.
Case-Control (n=120)
No
Is mean platelet volume associated with the degree of retinopathy in patients with diabetes mellitus?
Absolute Event Rate: 8.18% vs 7.52%
p-value: p=<0.05
Mean platelet volume is significantly elevated in patients with proliferative diabetic retinopathy, suggesting a potential role for platelet activity in the pathogenesis of diabetic microvascular complications.
Ateş et al. (2009) conducted a case-control in Diabetic retinopathy (n=120). Proliferative diabetic retinopathy vs. Healthy controls was evaluated on Mean platelet volume (MPV) in fL (p=<0.05). Mean platelet volume was significantly higher in patients with proliferative diabetic retinopathy compared to healthy controls (8.18 vs 7.52 fL, p<0.05) and positively correlated with the degree of retinopathy.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: