Why the study?
Do graded doses of atropine affect electrocardiogram intervals in normal volunteers?
Do graded doses of atropine affect electrocardiogram intervals in normal volunteers?
Atropine administration in normal volunteers affects R-T, P-R, and R-R intervals but not P wave duration.
May influence ECG monitoring with atropine; leaves open validation in patients and mechanistic studies.
Six normal volunteers were given graded doses of atropine. Analysis by a computer indicated that R‐T duration, P‐R segment, and R‐R intervals of the electrocardiograms were correlated, whereas the duration of the P wave was not dose related or linked to heart rate.
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Gravenstein et al. (1969) studied this question.
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