Why the study?
Does intravenous atropine alter cardiac output in healthy young men?
Does intravenous atropine alter cardiac output in healthy young men?
Intravenous atropine significantly increases heart rate with only a modest increase in total cardiac output, demonstrating that cardiac output per beat decreases when heart rate is artificially elevated without increased metabolic demand.
Atropine may reduce stroke volume despite modest minute output rise; leaves open effects in patients or with metabolic demand.
20 a.m.76 0.74 -21 144 3.27 4,400 58 May 6, 11:50 a.m. 66 0.77 -15 158 3.45 4,580 69 * 1 to 2 minutes before this time the subject received an intravenous injection of 1.2 mgm. atropine sulphate. Immediately thereafter the determination of the cardiac output was begun.
No takes yet. Share an insight, caveat, or question.
Smith et al. (1928) studied this question.
Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context: