Why the study?
Do intravenous atropine and isoproterenol affect cardiac output, central venous pressure, and indicator dilution volumes?
Do intravenous atropine and isoproterenol affect cardiac output, central venous pressure, and indicator dilution volumes?
Both atropine and isoproterenol increase cardiac output and decrease central venous pressure, demonstrating that cardiac output can rise via increased rate or stroke volume even when central venous pressure falls.
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May guide chronotrope use in low-output states despite low preload; leaves open prospective validation in contemporary cohorts.
GORTEX et al. (1961) studied this question.
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