Why the study?
Does intravenous flunitrazepam alter haemodynamic parameters in anaesthetized patients with valvular or coronary artery lesions compared to placebo?
Does intravenous flunitrazepam alter haemodynamic parameters in anaesthetized patients with valvular or coronary artery lesions compared to placebo?
Intravenous flunitrazepam causes significant reductions in systemic arterial pressure and cardiac output in anaesthetized patients with cardiac lesions.
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Flunitrazepam-associated hemodynamic depression warrants caution during cardiac anesthesia; leaves open effects versus placebo and impact on outcomes.
Hennart et al. (1982) studied this question.