Key result
On-pump beating heart CABG was preferentially selected for high-risk, unstable patients and was associated with a 4.4% mortality rate compared to 3.5% for on-pump arrested heart and 2.3% for off-pump procedures.
Why the study?
Does on-pump beating heart surgery provide a safe and efficacious alternative for unstable patients undergoing coronary artery bypass grafting?
Population
4,733 patients undergoing coronary artery bypass grafting (CABG) from January 2000 through December 2002
Comparison
On-pump beating heart coronary artery bypass… vs On-pump arrested heart CABG, off-pump CABG, and…
Design
Cohort
Follow-up
up to 30 days after surgery or discharge
Authors
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May support feasibility in high-risk unstable patients; leaves open comparative effectiveness versus off-pump CABG.
Observational (n=4,733)
No
Does on-pump beating heart surgery provide a safe and efficacious alternative for unstable patients undergoing coronary artery bypass grafting?
Absolute Event Rate: 4.4% vs 3.5%
p-value: p=0.04
On-pump beating heart CABG is a safe and efficacious alternative for high-risk, unstable patients, though it carries higher rates of certain morbidities compared to off-pump techniques.
Herbert et al. (2005) conducted an observational in Coronary artery disease requiring CABG (n=4,733). On-pump beating heart CABG vs. On-pump arrested heart CABG, off-pump CABG, and right heart assist CABG was evaluated on Mortality (p=0.04). On-pump beating heart CABG was preferentially selected for high-risk, unstable patients and was associated with a 4.4% mortality rate compared to 3.5% for on-pump arrested heart and 2.3% for off-pump procedures.