Key result
A simplified, high-throughput chromogenic assay using commercial human prothrombin complex was more sensitive and precise than some reported methods for measuring tissue factor procoagulant activity.
A new simplified, high-throughput chromogenic assay offers a more sensitive and precise method for screening tissue factor inhibitors.
No takes yet. Share an insight, caveat, or question.
May aid preclinical TF inhibitor screening; leaves open human assay validation and clinical utility.
Jiang et al. (2011) studied this question. Simplified high-throughput chromogenic assay vs. Reported methods for TF procoagulant activities was evaluated on Sensitivity and precision for TF procoagulant activities. A simplified, high-throughput chromogenic assay using commercial human prothrombin complex was more sensitive and precise than some reported methods for measuring tissue factor procoagulant activity.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: