Key result
Unconventional lipid ratios and indices, including AIP, CRI-I, CRI-II, AC, and CHOLindex, are positively associated with cardiovascular disease and can assist in predicting various CVD events.
Why the study?
Traditional lipid profile tests may be inadequate for predicting CVD risk, especially in intermediate risk, highlighting the need to evaluate diagnostic alternatives such as lipid ratios.
Do atherogenic indices (lipid ratios) improve the prediction of cardiovascular disease risk compared to traditional lipid profiles?
Do atherogenic indices (lipid ratios) improve the prediction of cardiovascular disease risk compared to traditional lipid profiles?
Answers are grounded in this paper and cite their sources.
Atherogenic indices such as AIP, CRI-I, CRI-II, AC, and CHOLindex can be easily calculated from standard lipid panels and may offer improved prediction of cardiovascular risk, especially in intermediate-risk patients.
Cardiovascular diseases (CVD) represent a major cause of mortality and morbidity worldwide. To date, many physicians still requesting traditional lipid profile tests (TG, TC, HDL-C, and LDL-C) to confirm the clinical diagnosis related to CVD. However, using these tests may be inadequate for the prediction of CVD risk, especially in intermediate risk. For better clinical practice, laboratory diagnostic alternatives should constantly be evaluated and developed by physicians and laboratory scientists. In this review, we sought to focus on the benefits of lipid ratios (CRI-, CRI-II, AIP, AC, and CHOLindex) in supporting clinical diagnosis and how they can be calculated. To attain this aim, a literature search in reputed databases (PubMed and Scopus) was performed and peer-reviewed research articles were included to conduct this review. Short theoretical and practical notes about each index were accordingly included along with calculation formulas. Thus, the current article can assist new researchers and young physicians to review what supports their knowledge in managing early CVDs.
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Abid et al. (2021) conducted a review in Cardiovascular diseases. Atherogenic indices (AIP, CRI-I, CRI-II, AC, CHOLindex) was evaluated. Unconventional lipid ratios and indices, including AIP, CRI-I, CRI-II, AC, and CHOLindex, are positively associated with cardiovascular disease and can assist in predicting various CVD events.
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