Key result
Elevated postoperative procalcitonin was a significant predictor of mortality (AUC 0.772; 95% CI 0.651-0.894) and complications, but did not specifically identify infections.
Why the study?
Does postoperative serum procalcitonin predict mortality, infections, and severe complications in high-risk patients after cardiac surgery on cardiopulmonary bypass?
Population
80 high-risk patients early after cardiac surgery on cardiopulmonary bypass, selected from a consecutive…
Design
Cohort
Follow-up
Hospital stay (hospital mortality)
Authors
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Elevated procalcitonin may flag mortality risk after cardiac surgery; hypothesis-generating for complications but should not yet guide infection-specific care.
Cohort (n=80)
Does postoperative serum procalcitonin predict mortality, infections, and severe complications in high-risk patients after cardiac surgery on cardiopulmonary bypass?
Effect estimate: AUC 0.772 (95% CI 0.651-0.894)
High postoperative procalcitonin levels are associated with increased mortality and severe complications after cardiac surgery, but cannot specifically differentiate between infectious and non-infectious complications.
Dörge et al. (2003) conducted a cohort in High-risk patients after cardiac surgery on cardiopulmonary bypass (n=80). Elevated postoperative procalcitonin (PCT) vs. Lower postoperative procalcitonin was evaluated on Mortality (AUC 0.772, 95% CI 0.651-0.894). Elevated postoperative procalcitonin was a significant predictor of mortality (AUC 0.772; 95% CI 0.651-0.894) and complications, but did not specifically identify infections.
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