Key result
Procalcitonin measured on day 1 after cardiac surgery predicted severe SIRS (85% sensitivity, 95% specificity) and late infection (100% sensitivity, 96% specificity).
Why the study?
Does procalcitonin measurement predict severe SIRS, late postoperative infection, and postoperative renal dysfunction in adult patients undergoing cardiac surgery with cardiopulmonary bypass?
Population
40 adult patients consecutively operated for a coronary or valve surgery with cardiopulmonary bypass
Design
Cohort
Follow-up
96 hours
Authors
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May aid early post-cardiac surgery risk stratification; hypothesis-generating and should not yet change practice.
Observational (n=40)
Does procalcitonin measurement predict severe SIRS, late postoperative infection, and postoperative renal dysfunction in adult patients undergoing cardiac surgery with cardiopulmonary bypass?
Procalcitonin is a fast-kinetic biomarker that can early predict severe SIRS, late postoperative infection, and postoperative renal dysfunction after cardiac surgery with cardiopulmonary bypass.
Kallel et al. (2012) conducted an observational in Coronary or valve surgery with cardiopulmonary bypass (n=40). Procalcitonin (PCT) measurement was evaluated on Diagnostic and prognostic value of PCT for severe SIRS, late postoperative infection, and postoperative renal dysfunction. Procalcitonin measured on day 1 after cardiac surgery predicted severe SIRS (85% sensitivity, 95% specificity) and late infection (100% sensitivity, 96% specificity).
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