Key result
A procalcitonin level above 2.95 ng/ml on the first postoperative day was associated with a significantly increased risk of delayed complications in patients with an initially uneventful course (adjusted OR 110.2).
Why the study?
Does a single postoperative measurement of procalcitonin predict delayed complications in patients with an initially uneventful course after elective cardiac surgery?
Cohort (n=751)
No
Does a single postoperative measurement of procalcitonin predict delayed complications in patients with an initially uneventful course after elective cardiac surgery?
Odds Ratio: 110.2 (95% CI 51.5–235.5)
p-value: p=<0.001
A single measurement of procalcitonin on the first postoperative day strongly predicts delayed complications in patients with an initially uneventful course after elective cardiac surgery.
No takes yet. Share an insight, caveat, or question.
May support early risk stratification after cardiac surgery; leaves open whether procalcitonin thresholds warrant prospective validation or management changes.
Klingele et al. (2016) conducted a cohort in Elective cardiac surgery (n=751). Elevated procalcitonin (>2.95 ng/ml) vs. Procalcitonin ≤2.95 ng/ml was evaluated on Combined adverse outcome (delayed complications defined as in-hospital death, ICU readmission, or prolonged length of hospital stay >12 days) (OR 110.2, 95% CI 51.5-235.5, p=<0.001). A procalcitonin level above 2.95 ng/ml on the first postoperative day was associated with a significantly increased risk of delayed complications in patients with an initially uneventful course (adjusted OR 110.2).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: