Transcatheter closure of patent ductus arteriosus in children weighing 5 kg or less: Initial experienc

Introduction: Trans-catheter closure (TCC) of patent ductus arteriosus (PDAs) is a well-establishednon-surgical method of closure. Objectives: To evaluate safety, feasibility & complicationsof device closure of patent ductus arteriosus (PDA) in small children weighing ≤ 5 kg with different types of devices for closure. Methods: patients with PDA underwent transcatheter closure, among whom 16 (33%) weighed 5 kg or less. All of these patients underwent transcatheter closure of PDA using an Amplatzer duct occluder I, Amplatzer duct occluder II or Amplatzer duct occluder 2 IIAS (Additional size) devices. Results: Sixteen patients (9 females & 7 males) between theages 20 days to 16 months had undergone device closures. Amplatzer Duct Occluder (ADOI) was used in 12 cases, 3 were closed with Amplatzer Duct Occluder (ADO2) and one the smallest of all (1.6 kg) patientwere selected for closure with Amplatzer Duct Occluder (ADO2 AS).At 1 month after the closure, the signs and symptoms improved markedly in all patients, and PDAs were completely closed and devices remained in situ on follow-up. Mild obstruction of left pulmonary artery (n=2) and aortic isthmus flow (n=1) was noted at the time of discharge which gradually improved on follow up. Conclusions: TCC of PDAin small babies 5 kg or less is feasible & safe alternative to surgical PDA closure in carefully selected patients. The immediate & short-term outcomes have proven this method to be safe & valid.