Why the study?
Does cardiac Doppler echocardiography accurately detect low-grade rejections compared to endomyocardial biopsy in heart transplant recipients?
Population
23 heart transplant recipients undergoing 345 endomyocardial biopsies
Comparison
Cardiac Doppler echocardiography measuring… vs Endomyocardial biopsies performed on the same day
Design
Cohort
Authors
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Cautions against relying on CDE alone for mild rejection surveillance; leaves open whether protocol optimization improves detection in heart transplant recipients.
Does cardiac Doppler echocardiography accurately detect low-grade rejections compared to endomyocardial biopsy in heart transplant recipients?
Cardiac Doppler echocardiography alone has low sensitivity (45%) for detecting mild rejections after heart transplantation and cannot replace endomyocardial biopsy.
Mouly-Bandini et al. (1996) studied this question.
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