Key result
Coronary artery disease was associated with significantly higher QTc dispersion compared to healthy subjects during morning and afternoon hours (p<0.001), though both groups showed a morning increase.
Why the study?
Does QT dispersion exhibit diurnal variation in patients with and without coronary artery disease?
Population
n=144 subjects, comprising 82 patients with coronary artery disease and 62 healthy subjects without coronary…
Comparison
Assessment of diurnal variation using 12-lead… vs Healthy subjects without coronary artery…
Design
Cross-sectional
Follow-up
1 day (morning, afternoon, and night recordings)
Authors
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Higher QTc dispersion in CAD may link to morning events; cross-sectional data leaves open prospective validation for risk stratification.
Cross-Sectional (n=144)
Does QT dispersion exhibit diurnal variation in patients with and without coronary artery disease?
p-value: p=<0.001
QT dispersion exhibits diurnal variation with morning increases in both healthy subjects and CAD patients, which may relate to the known morning peak in cardiovascular events.
Yetkın et al. (2001) conducted a cross-sectional in Coronary artery disease (n=144). Coronary artery disease vs. Healthy subjects without coronary artery disease was evaluated on QTc dispersion at different times of day (p=<0.001). Coronary artery disease was associated with significantly higher QTc dispersion compared to healthy subjects during morning and afternoon hours (p<0.001), though both groups showed a morning increase.
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